The body of a young woman is found in a dumpster in Chicago and detectives Andy Polanski and Frank Campello are charged with finding the killer. The two are polar opposites. Polanski is the son of a disgraced Chicago police officer and is fastidious about his reputation. He has also recently been transferred from another district having blown the whistle on some corrupt cops. Campello, however, takes a live-and-let-live approach to his life and job.

It soon becomes clear, as another young woman--a potential witness--is murdered, that a sex-trafficking operation in Chicago is preying on illegal aliens. As the ill-matched pair dig deeper, an influential alderman and his son are implicated. Then Polanski is framed for a narcotics offense, devastating the cases against the corrupt officers and the alderman. Only when Campello is challenged by a local minister, whom he meets when visiting Polanski, does he find the motivation to seek justice.